Butyrate For Weight Loss, Appetite Control, & Type 2 Diabetes

Butyrate is a powerful compound for Fat & Weight loss

A growing body of scientific evidence points to this one increasingly  undeniable reality.

I know you are eager to hear more about today's content around butyrate for body weight control but before we jump into that just a friendly reminder that GutArmor has a 6-step guide on how to naturally increase butyrate producing bacteria that you’ll absolutely want to check out.

With that said, let's get to the good stuff.

Butyrate , Body Weight & Appetite Regulation

Short Chain Fatty Acids (SCFAs), particularly butyrate, have long gained scientific interest for their role in appetite regulation.

There is little questioning the fact that appetite regulation plays an incredibly important role in human health and daily life, but how is it that these particular compounds contribute to this important function?

There are a few things to consider here:

  • Butyrate may activate cellular signaling pathways that increase the production of hormones like GLP-1, PYY and leptin – all of which are known for their appetite suppressing effects.
  • Butyrate may cross the BBB (blood brain barrier) and directly interact with neurons responsible for appetite control.

But wait, there’s more.

In a 2021 paper published out of Molecules, the scientists involved singled out butyrate for a uniquely beneficial role in the realm of weight.

They identified, based largely on pre-clinical data, several additional ways butyrate might help with bodyweight regulation.

These include:

  • Improved fat metabolism*
  • Decreased inflammation
  • Improved liver function (liver and gut health are tightly connected)
  • Decreased cholesterol production
  • Improved insulin sensitivity (see next section for more on this!)

*Current scientific evidence suggests that SCFAs like butyrate stimulate our body to utilize fat as fuel and increase energy expenditure without changes to caloric intake or physical activity, which is why they’ve gained scientific interest in the world of body weight management.  

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Butyrate & Type 2 Diabetes

Close to 1 in 10 Americans are living with type 2 diabetes, a condition which greatly increases one risk of heart disease and other undesirable health outcomes.

It is only in the last several years, however, that science has began to draw a strong link between diabetes and the human gut microbiome.

We now have a greater appreciation for the fact that SCFAs like butyrate play an important role in carbohydrate metabolism and the maintenance of healthy blood sugar levels.

Case in point, a recently published study out of JAMA found that adults with higher levels of butyrate-producing gut bacteria were less likely to have type 2 diabetes and insulin resistance whereas those living with type 2 diabetes tend to have lower levels of these beneficial bacteria.

Vitamin D3 & Butyrate Producing Bacteria

Let's not forget that GutArmor delivers 3000IU of Vitamin D3.

About 1 in 6 Americans have inadequate Vitamin D levels, and it is certainly possible that this number is likely higher for those who live in the Northern States – particularly during and shortly after the winter months (AKA right now!) or in those who don’t regularly consume fish, eggs & milk (the main sources of D3, especially fatty fish like salmon which has by far the most).

There is human evidence available to us which suggests that when those with inadequate Vitamin D3 levels supplement Vitamin D their production of healthy butyrate producing bacteria increases.

Final Thoughts

It’s clear to anyone paying attention that optimizing the state of one’s gut microbiome, which includes the levels of butyrate producing bacteria and butyrate in general, is beneficial to human health.

In today’s post we provide evidence that these benefits extend into the world of weight and appetite management as well as type 2 diabetes management and risk reduction.

This is only the start of the story though.

Check out our 6-step guide to enhancing the presence of butyrate in your GI tract and to learn more about how postbiotic tributyrin, as delivered by GutArmor, contributes meaningfully to that cause.

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Butyrate, the key to Gut health & Weight Loss